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Section: Hemostasis
2.4 Inhibitors, Thrombotic Disorders, and Anticoagulant Drugs

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Which therapy and resulting mode of action are appropriate for the treatment of a patient with a high titer of factor VIII inhibitors?
Factor VIII concentrate to neutralize the antibodies
Recombinant factor VIIa (rVIIa) to activate factor X
Factor X concentrate to activate the common pathway
Fresh frozen plasma to replace factor VIII